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Scholars Journal of Medical Case Reports | Volume-8 | Issue-09
Familial Central Nervous Malignancies Focus on Spinal Meningioma: Incidence in First Degree Relative
Dr. Manmeet Pal Kaur, Dr. Niten K Garg, Dr. Kanika Kinra, Dr. Venus Sharma
Published: Sept. 30, 2020 |
179
113
DOI: 10.36347/sjmcr.2020.v08i09.015
Pages: 864-867
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Abstract
Meningiomas are extramedullary, intradural tumors arising from meningothelial arachnoid cap cells within the spinal dura. Spinal meningiomas are the most common spinal tumors in adults, accounting for up to 38% of intradural spinal tumors but only for 6.5% of overall craniospinal tumors in the adult age group. Similar histological subtypes are observed in both intracranial and spinal meningiomas, including meningothelial, metaplastic, psammomatous, transitional, atypical, and clear cell types. Multiple genes have been associated with spinal meningiomas like deletion of chromosome 22q and of its associated gene NF2 in cases of spinal meningioma. We are presenting a case of Intradural meningioma in a 30 year old female and her 50 year old mother.