DOI: 10.36347/sjmcr.2020.v08i10.004

Pages: 882-885

Antiphospholipid syndrome (APS) is a complex disorder and associated with thrombosis which causes significant morbidity with antiphospholipid antibodies (aPL). Many percentages of patients with the systemic lupus erythematosus (SLE) were tested positive for aPL antibodies. However, patients in the early stage do not report to have SLE symptoms. In the present case, the primary APS antiphospholipid antibodies were present with multiple deep vein thrombosis. A 24-year-old female patient was admitted to the hospital for the complaints of excruciating pain over the left lower limb and swelling that extended till the groin. Further, the investigations were confirmed antiphospholipid syndrome through positive results of tests for anti-cardiolipin (ACLA), anti-nuclear antibody (ANA) and beta-2 glycoprotein. However, the presence of SLE is confirmed only by direct coombs test. In this case, SLE with APS antibody not triggered the syndrome, and there were no signs of any SLE syndrome, however, patients had multiple deep vein thrombosis and underwent for the catheter-directed thrombolytic procedure. In the present case, early diagnosis and sufficient treatment are required to prevent the progression of the disease.