DOI: 10.36347/sjams.2015.v03i08.008

Pages: 2773-2778

Smoking is a major health hazard, with detrimental effects on many organs, including skeleton. There are limited international and local data about the effect of cigarette smoking on the serum levels of calcium and phosphate and hence its effect on the skeleton. Therefore, the aim of this study was to evaluate the effect of cigarette smoking on the serum levels of calcium and phosphate, compared to apparently healthy individuals (non cigarette smokers) as a control group. In methodology 105 cigarette smokers and 105 apparently healthy controls were enrolled into the study (all were males).The mean age of the cigarette smokers was 38.6 years (range 20-60), while it was 39.1 years (range19- 58) in the control group. The difference was not statistically significant (P=0.097), Serum levels of calcium, phosphate, were measured using Roche Diagnostic/Hitachi 902 analyzer. In results Showed significant differences between the means of serum calcium, phosphate in the case group and the control group (mean ± SD): (8.71 ± 0.32) versus (9.66 ± 0.51) mg/dl, P=0.012, (3.74 ± 0.52) versus (2.82 ± 0.38) mg/dl, P=0.032. In Conclusion cigarette smoking is lead to increase of calcium while reduced of phosphate levels in cigarettes smokers.