DOI: 10.36347/sjams.2016.v04i01.022

Pages: 124-128

This is a hospital based study comparing the five most common diagnostic modalities for coronary artery disease, ECG, ETT, Rest and Stress Echo, 99mTc-MIBI, and Angiography, taking Angiography as the gold standard. Seventeen patients were included in the study, 16 were males and one was female. In each patient, corresponding resting and stress 99mTc-MIBI images were evaluated for direct comparison. Data analysis was done qualitatively (visual analysis) by three independent nuclear physicians (1). Echocardiography and angiography were performed and analyzed by a cardiologist. (2). Place of Study: Nuclear Medicine, Oncology, and Radiotherapy Institute (NORI), Islam Abad, Pakistan. (3). ECG sensitivity was found to be relatively low (60%) compared to the others. Echo sensitivity was 82.4%. Stress induced a significant improvement in sensitivity of both ECG and Echo. 99mTc-MIBI sensitivity and specificity obtained were comparable to those of Angiography. In addition, the localization ability for diseased coronary arteries by the different modalities was also investigated in which ECG and Echo showed fair results for localization of LAD problems, average results for RCA and poor results for LCx. 99mTc-MIBI showed good results for LAD, excellent results for RCA, and below average results for LCx artery diseases.