DOI: 10.36347/sjams.2016.v04i01.023

Pages: 129-132

Non-alcoholic fatty liver disease (NAFLD) refers to the accumulation of hepatic statuses not due to excess alcohol consumption. NAFLD is the most common liver condition in the world. NAFLD is shown to be associated with obesity, type 2 diabetes, dyslipidemia and hypertension. The thyroid gland is significantly involved in energy homeostasis, lipid and carbohydrate metabolism, regulation of body weight and adipogenesis. In recent years, growing body of evidence has led to speculation on the association between NAFLD/NASH with thyroid dysfunction. The main of this study was 1. To find out correlation of NAFLD with BMI and THS in general population by means of noninvasive methods. 2. To evaluate BMI and THS as a risk factors for the development of NAFLD in general population. The material and methods were total of 500 cases of age 30 to 65 yrs of both genders visiting Medicine OPD of SAMC & PG Institute, Indore over a period of 1½ yrs were included in the study. Anthropometric data were collected. TSH was done in all subjects and USG of abdomen was done in all subjects too see the evidence of NAFLD. The results of the study showed a co-relation between BMI and NAFLD. Among 138 cases with NAFLD out of 500 cases that were under study the mean BMI with SD was found to be 25.39±5.44 and cases without NAFLD the mean BMI with SD was found to be 22.42±3.11 (with p-value of 0.000). The study showed that mean TSH in cases with fatty liver was 2.75±3.02 mg/dl and in those with no fatty liver the mean TSH was 4.5±13.4 mg/dl (with p-value 0.135). In conclusion The BMI is having positive correlation with NAFLD in our study so that public health initiatives and long term preventive strategies hold the key to halt or reverse the pandemic of obesity and possible onset of NAFLD in our society.