DOI: 10.36347/sjds.2019.v06i11.003

Pages: 484-492

Periodontitis and liver diseases significantly influence the health. Numerous studies were investigated the relationship between periodontitis and hepatic diseases. The purpose of the present study designed to evaluate the effect of non-surgical periodontal therapy on serum levels of several liver function tests in systemically healthy individuals. Twenty moderates to severe chronic periodontitis (CP) patients (diseased group) and fifteen periodontally healthy subjects (control group) were involved in present research. The diseased group evaluated clinically by the following: Plaque and Bleeding Index (PI, BI), Pocket depth (PD) and Clinical Attachment Level (CAL) at baseline and 1 month after periodontal treatment. Serum levels of liver function tests; Total protein (TP), Albumen (ALB), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Alkaline Phosphatase (ALP) plus to direct and total Bilirubin (BIL-D and BIL-T) were analyzed for all diseased and healthy participants. Statistical analysis revealed highly significant improvement of clinical parameters (BI, PD, CAL) (P<0.01) and significant difference for (PI) (P<0.05) when comparing the baseline to 1 month after periodontal therapy. Biochemical assaying showed enhancement in levels of all liver function tests at 1 month versus to baseline of treatment, highly significant differences for TP (P<0.01) and significant differences for ALB (P<0.05), the other tests became non-significant (P0.05). When comparing of diseased group at baseline versus healthy control subjects, the TP and ALB appeared highly significant differences (P<0.01), the other tests increased in diseased patients than healthy subjects but the differences are non-significant (P0.05). Furthermore, there was a significant correlation (r= -0.562) between PD and TP only at 1 month after initial therapy. The obtained results suggested that the periodontal therapy might had a beneficial effect on liver health. Further researches needed t