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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-02
Role of Diffusion Weighted MRI in Prostatic Lesions
Dr. AlkaAgrawal, Dr. P.S Tripathi, Dr. KrunalVaghasia, Dr. Vibhu Goel, Dr. UrvashiGarg
Published: Feb. 26, 2016 | 83 54
DOI: 10.36347/sjams.2016.v04i02.022
Pages: 411-419
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Abstract
Prostate cancer is 2nd most common cancer in adult Indian males and is a potentially curable disease when diagnosed in early stages. Multiparametric MRI is a competitive and comprehensive modality for assessing the morphology and functional characteristics of the prostate in cases of diffuse and focal prostatic disease. 50 patients with Lower urinary tract symptoms and abnormal USG underwent non-contrast MRI. T1w, T2w and Diffusion weighted images were taken and ADC values were calculated using ADC maps. When a cut off ADC value of 1.4 x 10-3 mm2/s is applied to prostatic lesions, and the results obtained are added to the anatomical details obtained from T1WI & T2WI, there is a considerable increase in the Specificity, Sensitivity, PPV and NPV. Due to the very high accuracy, non-contrast MRI with the help of diffusion weighted imaging and the corresponding ADC values can obviate the need for multiple diagnostic procedures and can act as a one stop shop for diagnosing all the prostatic lesions, both for its identification and characterization.