DOI: 10.36347/sjams.2016.v04i02.025

Pages: 434-437

After development of the testis in the abdominal cavity, if its descent is arrested anywhere along its normal pathway of migration undescended testis results. Undescended testis is a multifactorial disease as the specific mechanism and factors involved in testicular descent are partly obscure. In addition to infertility, undescended testis is highly susceptible for malignant transformation. This study was designed to survey the various histopathological changes of undescended testis in pediatric age group. For this purpose we have evaluated testicular biopsy specimens from 116 boys with undescended testis who were treated surgically. Microscopic examination showed that in undescended testis the epithelium of the seminiferous tubules undergoes extensive atrophy with maturation arrest and significant reduction of germ cells while the interstitial cells are actually found to be increased in numbers. The longer the testicle resides outside the scrotum, the greater the chances of harm to the seminiferous tubules. This study suggests early orchiopexy and promotes importance of testicular biopsy for providing valuable prognostic information.