DOI: 10.36347/sjams.2016.v04i03.008

Pages: 669-673

Kidney tumour may be benign or malignant, exact diagnosis of which is necessary for proper treatment. Immunohistochemistry may be needed for correct diagnosis of few discordant cases. In methodology the study was done on 45 patients with kidney tumour who underwent radical nephrectomy. Histopathological examination and immunohistochemistry with CK7 and Vimentin was done on their nephrectomy specimen. In results Among 45 cases, 39 were renal cell carcinoma, three angiomyolipoma, two oncocytoma and one cystic nephroma. Clear cell renal cell carcinoma was the commonest tumor with 72% cases, followed by papillary RCC 21% and chromophobe RCC 5%. CK7 was positive in 14.2% clear cell RCC, 87.5% papillary RCC and 100% chromophobe RCC and was negative in oncocytoma. Vimentin was positive in 100% clear cell RCC and papillary RCC. It was negative for oncocytoma and chromophobe RCC. P-values for both the cases are significant. The concusion was RCC is the most common malignant kidney tumour among which clear cell carcinoma is the commonest subtype. Histopathological diagnosis is sufficient but CK7 and Vimentin can be used as adjunct or to conclude few discordant cases.