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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-03
Efficacy of Bupivacaine with 8 mg Dexamethasone as an adjuvant for Supraclavicular Brachial Plexus Block by comparing with 0.25% Bupivacaine alone
Dr. Srihari Babu Gonuguntla
Published: March 26, 2016 |
143
172
DOI: 10.36347/sjams.2016.v04i03.013
Pages: 691-695
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Abstract
Peripheral nerve blocks came into rise now-a-days because of more advantages on general anesthesia. Steroids
are in use as an adjuvant for local anesthetics since many years, as steroids have the effects of anti-inflammatory and
analgesia. For Brachial plexus block, Group A and Group B patients were administered with 40 ml of 0.25% of
bupivacaine with 2 ml of normal saline and 40 ml of 0.25% Bupivacaine with 8 MG Dexamethasone respectively
through Supraclavicular approach. Onset, duration of sensory and motor blockade, duration of postoperative analgesia,
postoperative nausea and vomiting effects were observed and assessed. Statistical analysis was done using Graphpad
software. There was significantly increase in duration of both sensory and motor block in Group B when compared to
Group A. Among Group A and Group B patients duration of postoperative analgesia was 213.4±34.2 minutes and
642.6±21.2 minutes respectively. Duration of Postoperative analgesia is a significant factor which was shown
statistically. Postoperative nausea and vomiting was predominant in Group A when compared to Group B. It was about
30% and 6.6% respectively. Dexamethasone as an adjuvant to Bupivacaine offers many advantages than bupivacaine
alone. Bupivacaine dexamethasone group increased duration of postoperative analgesia, reduced gastrointestinal side
effects and pentazocine requirement as an analgesia when compared to bupivacaine group.