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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-03
A Study to assess the profile of multidrug-resistant tuberculosis (MDR-TB) in tertiary care hospital setting
Dr. Vikas Kumar Mishra, Dr. Prerna Gupt, Dr. Pradeep Pachar, Dr. Suresh Kumar Jangir, Dr. Rakesh C. Gupta, Dr. Neeraj Gour
Published: March 29, 2016 | 39 58
DOI: 10.36347/sjams.2016.v04i03.041
Pages: 820-827
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Abstract
Drug resistance is a threat to TB control programs worldwide. Patients infected with multiple-drug resistant strains are less likely to become cured. This study was conducted to assess the profile of multidrug-resistant tuberculosis (MDR-TB) in tertiary care hospital setting, Ajmer, Rajasthan India. In methodology A total of 244 cases of Multidrug Resistant Pulmonary Tuberculosis registered under RNTCP (Revised National Tuberculosis Programme) for Cat IV regimen from 1st January 2012 to 30th September 2012 at PMDT site at Department of Respiratory Medicine, JLN Medical College and Associated Group of Hospitals, Ajmer, Rajasthan were included results Out of 244 patients, 62 (25.4%) patients belong to MDR Suspect Criteria A, 176 (72.1%) patients belong to MDR Suspect Criteria B, and 6 (2.5%) patients belong to MDR Suspect Criteria C. Out of 244 patients, 60 (24.6%) patients had documented h/o contact with TB patients, of which 53 (88.3%) patients had h/o contact with PTB patients, whereas 7 (11.7%) patients had h/o contact with MDR TB patients. According to radiological finding, 224 (91.8%) patients had bilateral lung disease, while 20 (8.2%) patients had unilateral lung disease. In conclusion the Health education regarding spread of disease, early detection of MDR-TB by strengthened laboratory support, effective therapy, implicating innovative control measures, and applying them specially among immigrants, would interrupt the ongoing transmission and control this emerging epidemic.