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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-03
Amlodipine induced gingival enlargement managed by a combined approach
Muzafar Ahmad Bhat, Khan Rafiya N, Mufeed Ahamd Bhat
Published: March 30, 2016 |
129
146
DOI: 10.36347/sjams.2016.v04i03.077
Pages: 1029-1031
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Abstract
Gingival overgrowth represents an over-exuberant response to a variety of local and systemic conditions.
Certain anticonvulsants, immuno-suppressive drugs and a number of calcium channel blockers have been shown to
produce similar gingival overgrowths in certain susceptible patients. Amlodipine, a third generation calcium channel
blocker, used mostly as an anti-hypertensive drug has been shown to promote gingival overgrowth, although reported in
very limited cases. A rare case of amlodipine-induced gingival overgrowth has been reported herein in a 55-year-old
male patient. The treatment aspect included Phase-1 therapy, substitution of the drug, the surgical excision and the
maintenance and supportive therapy resulting in excellent clinical outcome.