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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-04
Diagnostic value of the biochemical parameters in patients with empyema thoracis
Meral Ekim, Hasan Ekim
Published: April 26, 2016 |
163
108
DOI: 10.36347/sjams.2016.v04i04.003
Pages: 1112-1115
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Abstract
Empyema thoracis means an accumulation purulent effusion in the pleural cavity. Its incidence has gradually
decreased because of the increased availability and use of antibiotics. However empyema still continues to be a
significant cause of morbidity, especially in developing countries. The purpose of this study was to examine the
diagnostic value of pleural effusion LDH, glucose concentration and pH in patients with purulent pleural effusion.
Between November 2005 and August 2012, 20 patients with empyema thoracis admitted to Dursun Odabas Medical
Center were included in the study. Patients who had developed empyema thoracis associated pulmonary resection,
tuberculosis, or traumas were not included in the study. After the thoracentesis, a specimen was collected to a tube for
biochemical analysis (glucose, protein and LDH). A second sample was taken into a heparinized syringe for pH analysis.
Pleural aspiration was initially performed in all patients. Most patients required closed chest tube drainage. Decortication
was performed, if chest tube drainage failed. There were 18 male and 2 female patients. The age of patients ranged from
2 to 67 years, with a mean age of 29.17±18.52 years. The samples of pleural effusion had had a high protein and LDH
levels, but low pH and glucose levels. Pleural aspiration was found successful treatment method only in two patients
(10%). Tube thoracostomy was required in 18 patients, of whom four had thoracotomy. Diagnosis of empyema thoracis
can be supported by biochemical analysis of pleural effusions. Underwater seal drainage plus antibiotic therapy can cure
the empyema in majority of the patients. Treatment should be started without delay if the biochemical markers are
positive.