DOI: 10.36347/sjams.2016.v04i04.051

Pages: 1379-1383

Malaria is a parasitic disease in tropical and subtropical climates. It causes a number of life-threatening complications including cerebral malaria, pulmonary edema, organ failure (kidneys, liver, or spleen), hypoglycemia and anemia. The study was conducted on 30 adult’s patients with recurrent falciparum malaria and 41 adults healthy individuals at New Halfa (Sudan) during the period from 2008 to 2010. The aim of the study was to evaluate the effect of recurrent falciparum malaria on the plasma protein patterns. Serum protein was analysed by electrophoresis and photometric method. The mean values in g/dL ± SD of the different patterns in the patients group are as follows; Total protein: (7.34 g/dL ± 0.59 ), Albumin: (3.32 g/dL ± 0.48), α-1: (0.55 g/dL ± 0.27), α-2: (1.45 g/dL ± 0.50), β-1: (1.02 g/dL ± 0.32), β-2: (0.70 g/dL ± 0.32), and γ globulins: (0.78 g/dL ± 0.53). Only nine sera of the patients group were found to show β-2 fraction (mean 0.70 g/dL SD ± 032). The mean values in g/dL± SD of the different patterns in the control group are as follows; Total proteins: (7.29 g/dl ± 0.61), albumin: (4.01 g/dl ± 0.54). α-1: (0.27 g/dl ± 0.12), α-2: (1.26 g/dl ± 0.46), β-1: (0.94 g/dl ± 1.02), β-2: (0.57 g/dl ± 0.18), and γ- globulins: (0.84 g/dl ± 0.18). The study revealed that there was a significant difference in the albumin and α-1 levels between the patients and the control (P value = 0.000). In conclusion, falciparum malaria group showed lower albumin higher α-1 levels when compared to the control.