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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-04
Comparative study of topical diltiazem sphincterotomy and lateral internal sphincterotomy in the treatment of chronic fissure-in-ano: a prospective analytical study
Anupam Choudhary, Pawan Katti, K. Krishna Prasad
Published: April 30, 2016 |
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119
DOI: 10.36347/sjams.2016.v04i04.055
Pages: 1402-1405
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Abstract
Anal fissures are considered to be one of the commonest causes of proctalgia. Chronic fissure-in-ano is the
condition when there is persistence of fissure for more than six weeks. Surgical techniques like manual anal dilatation or
partial lateral internal sphincterotomy effectively heal most fissures, but may result in incontinence. Hence the search for
alternative treatment options that includes pharmacological agents such as topical diltiazem, that doesn’t result in
disabling incontinence. The objective was to study the efficacy of topical diltiazem sphincterotomy for chronic fissure-inano. To study the efficacy of Lateral internal sphincterotomy for chronic fissure-in-ano. To compare the efficacy of
Topical Diltiazem sphincterotomy with Lateral internal sphincterotomy in terms of relief of symptoms, healing of fissure,
and complications. The study includes 70 symptomatic Patients, suffering from Chronic Fissure-in-ano attending the
Dept. of Surgery R.L.J. Hospital & RC and attached hospitals, Kolar, during the period from October 2012 to May 2014.
These seventy patients were divided into Group-P (Pharmacologic Group/ Topical Diltiazem group) and Group-S
(Surgical Group/ Lateral Sphincterotomy group) of 35 patients each by odd & even method. Patients are followed up at
2nd, 4th and 6th weeks for assessment of healing of fissure, pain relief and incontinence. Statistical analysis for P value is
done by chi-square test. In Results In the present study, male/female ratio is 1.8:1; Peak incidence for development of
fissure-in-ano was the fourth decade of life. Pain and bleeding during defecation were the commonest complaint. All
patients complained of constipation. 98.6% of patients were consuming mixed diet. Relief of symptoms was 82.8% with
group-p and 97.14% with group-s which was statistically significant with p value 0.04.