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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-05
Effects of Soy-flour Enriched Diet on the Testis and Gonadal Hormone Status of Male Wistar Rats
Adesanya O.A, Oyesola O.A, Adesanya R.A, Bamitale K.D.S, Odubela O.O
Published: May 29, 2016 |
133
110
DOI: 10.36347/sjams.2016.v04i05.040
Pages: 1657-1661
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Abstract
This study was designed to determine the effects of soy-flour enriched diet on the testis morphology, gonadal
hormones (Testosterone and FSH) and accessory sex glands (prostate and seminal vesicle) semen count and motility in
rats. Fifteen male rats were fed raw soy-flour enriched diet at 0% W: W, 10% W: W 20% W: W (soy flour / milled
standard feed by weight) for eight weeks. The sperm count and the weight of accessory sex glands were measured. There
was a significant decrease in the weight of the testis, seminal vesicle, and the prostate (P < 0.05) compared with the
control. There was also significant decrease in the sperm count and testosterone level in a dose dependent manner. The
testis histo-architecture was normal and the seminferous tubules were shrunken compared to the control in both the high
dose and low dose. Raw soy-flour supplementation with standard feed produces a form of mild toxic effect on the testis
histo-architecture.