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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-05
Effects of Soy-flour Enriched Diet on the Testis and Gonadal Hormone Status of Male Wistar Rats
Adesanya O.A, Oyesola O.A, Adesanya R.A, Bamitale K.D.S, Odubela O.O
Published: May 29, 2016 | 51 48
DOI: 10.36347/sjams.2016.v04i05.040
Pages: 1657-1661
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Abstract
This study was designed to determine the effects of soy-flour enriched diet on the testis morphology, gonadal hormones (Testosterone and FSH) and accessory sex glands (prostate and seminal vesicle) semen count and motility in rats. Fifteen male rats were fed raw soy-flour enriched diet at 0% W: W, 10% W: W 20% W: W (soy flour / milled standard feed by weight) for eight weeks. The sperm count and the weight of accessory sex glands were measured. There was a significant decrease in the weight of the testis, seminal vesicle, and the prostate (P < 0.05) compared with the control. There was also significant decrease in the sperm count and testosterone level in a dose dependent manner. The testis histo-architecture was normal and the seminferous tubules were shrunken compared to the control in both the high dose and low dose. Raw soy-flour supplementation with standard feed produces a form of mild toxic effect on the testis histo-architecture.