DOI: 10.36347/sajb.2018.v06i01.003

Pages: 14-21

Bacterial resistance is the cause of morbidity and mortality worldwide, particularly in Africa. However, data on antimicrobial susceptibility patterns are limited in many countries such as Gabon. 234 clinical isolates were screened for their resistance against usual antibiotics by using BioMerieux ATB test strips, ATB G, ATB-Staph and ATB-Strep; Mycoplasma IST 2 test strips (BioMérieux, France) and Vitek 2 compact automaton. E. coli (29.49%) was the most common pathogen causing various diseases isolated, followed by U. urealyticum (27.35%), K. pneumonia (14.96%), P. mirabilis (3.42%) and P. aeruginosa (2.56%). S. aureus is Gram + the most represented with 6.84%. 28.65% of Enterobacteriaceae isolates were resistant to antibiotics tested. Imipenem (β-Lactamine) and Amikacin (aminoglycoside) were the most effective antimicrobial agents, with susceptibility rates of 94.92% and 91.67%, respectively. Ampicilin and Amoxicillin were the least effective, with susceptibility rates of 19.09% and 37.58%, respectively, against Enterobacteriaceae. 68.75% isolates of S. aureus were phenotypically resistant to methicillin. U. urealyticum isolates were resistant to Clarythromycin (59.26%), Erythromycin (57.41%), Ciprofloxacin (53.7%) and Azithromycin (51.86%). Knowledge of bacterial ecology and monitoring of antibiotic resistance are needed to guide antibiotic therapy in our environment.