DOI: 10.36347/sajb.2015.v03i01.001

Pages: 1-2

Thyroid hormones have profound effects on reproduction and pregnancy. There seems to be an association of thyroid dysfuntion with prolactin levels and decrease fecundity. This study was undertaken to review the correlation of prolactin levels and thyroid status and fertility of subjects. Eighty (80) women with primary infertility attending gynae OPD were evaluated. Eighty (80) fertile women with similar age and socioeconomic status were taken as controls. The association of thyroid dysfunction and serum prolactin was reviewed. There was positive correlation between infertility and serum TSH and prolactin levels. Hyperprolactinemia was found in 27% of infertile women while it was only 8% in control group. Serum T3 and T4 level were significantly decreased in infertile females as compared to fertile females In our study, there was high prevalence of thyroid disorder and hyperprolactinemia in infertile women. There was significant association between serum T3, T4,TSH and prolactin level in infertile women.