DOI: 10.36347/sajb.2015.v03i02.005

Pages: 143-149

A wound is a trauma to any tissue of the body especially that which is caused by physical means and interruption of continuity which normally heals rapidly without difficulty. Wound healing is an intricate process in which the skin (or another organ) repairs itself. In the course of this study, 24 male wistar rats weighing approximately 175g were used in this research. The rats were separated into two groups with 12 animals each in the Lycopersicon esculentum fruit and the gentamicin groups. A wound size of 2cm by 2cm which exposed panniculus adiposus was inflicted on the dorsolateral shaved aspect of the thorax after anaesthetisa. The wound sizes were immediately measured using a 4cm by 4cm square template transparent sheet placed on a graph sheet. The wounds were then dressed with the L. esculentum fruit paste and gentamicin ointment. The result showed non statistical significant difference in the % percentage wound contraction excepting at day 8; the wound healing cells at day 8 and the wound closure day. This study has therefore revealed both therapeutic agents to promote wound healing activity.