DOI: 10.36347/sajb.2015.v03i02.008

Pages: 161-165

Maternal total homocysteine concentrations have been linked to a wide range of adverse pregnancy outcomes and could possibly influence birth weight. Keeping this in mind the present study was done to find the association of serum levels of homocysteine with neonatal birth weight in Department of Obstetrics and Gynaecology, SMS Medical College, Jaipur. It was a hospital-based analytical study. 162 pregnant women with gestational age of 28 weeks or more, normotensive or with pre-eclampsia were included. S homocysteine levels were measured and results were analyzed to find association of homocysteinewith neonatal birth weight. At normal homocysteine level (5-15 3 mol/L) mean neonatal weight was 2.60 ± .39 kg. Mean neonatal weight decreases as the maternal serum homocysteine concentration increases. The difference in the neonatal weight, in various groups was statistically significant (p - 0.01). There was a negative correlation between neonatal birth weight and serum homocysteine levels. Serum homocysteine levels have a negative correlation with neonatal birth weight. With normalisation of elevated homocysteine levels we can provide better maternal and perinatal outcome.