DOI: 10.36347/sjams.2016.v04i06.062

Pages: 2173-2176

Urinary tract infections (UTI) are among the most common bacterial infections occurring both in males and females encountered in clinical practice and account for significant morbidity and high medical cost.UTI are more common, more severe, and carry worst outcome in patients in Diabetes Mellitus. For this reason, we have evaluated the spectrum of uro pathogens and the profile of antibiotic resistance in both diabetics and non-diabetic patients with UTI with aim to study and assess the pervalance of UTI among diabetics and non-diabetics attending the Medicine Department of Rajiv Gandhi Institute of Medical Sciences (RIMS) and also to identify the most frequent bacteria responsible for UTI.A total of 475 cases attending IP & OP Department of Medicine at RIMS, Adilabad, over a period of one year ranging from February 2015 –January 2016 were screened for this study. Among these 150 diabetic patients (males:65 and females:85), and 135 non-diabetic patients (males:55 and females:80) who were culture positive for uro pathogens were studied.About 28% of the patients, both diabetic and non-diabetic presented with asymptomatic bacteriuria and presence of pyelonephritis was higher among diabetics compared to non-diabetics. The isolation rate of Escherichia coli (E.coli) from urine cultures among diabetic patients was higher (63%) followed by Klebsiella (15%) and Enterococcus (11%) while in non-diabetic patients, isolation of E.coli was 57% followed by Enterococcus (17%) and Klebsiella (17%). Elevated glucose levels in diabetics pre-disposed to UTI with E.coli being the most common uropathogens. Therefore, for prevention of complications, investigation for uropathogens in diabetics with UTI is very important.