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Abstract – The side effects resulted due to the therapy of classical Non-steroidal anti-inflammatory drugs (NSAIDs) and the opoids in the management of pain and inflammatory conditions are major problems. Researches have been carried out still inorder to have novel analgesic, anti-inflammatory agents with no side effects. As plants based medicines are found with minimal side effects, they have gained much attention in this regard. This review article is a try to provide an overview of reported analgesic and anti-inflammatory activities of fifteen plants with interesting profile of activities.

Abstract – The present study aimed for evaluation of Aquilaria agallocha oil obtained by hydro-distillation from the woods for in-vivo and in-vitro anti-inflammatory activity. The oil was screened for in-vivo anti-inflammatory activity by carrageenan-induced paw edema in rat model and In-vitro anti-inflammatory activity by human red blood cell membrane stabilization method. The potency of the oil was compared with standard Diclofenac (10 mg/kg). The oil showed significant reduction of edema in carrageenan induced rat paw edema model maximum at 3 hr for AAO 50 mg/kg, AAO 100 mg/kg and diclofenec 10 mg/kg (% reduction in paw volume 58.59%, 62.11% and 68.94% respectably) and membrane stabilizing action on human red blood cell membrane at concentration of 100, 250 and 500 mcg/ml showed 39.66%, 62.94% and 78.50% which are comparable with standard diclofenec.

Abstract – The present study aimed evaluate the protective effect of citrullus lanatus seed oil against CCl4 induced hepatic damage in rat. The hepatoprotective was on carbon tetrachloride induced hepatotoxicity in rats by estimated serum hepatic enzyme levels and hisopathological study of liver tissues. Citrullus lanatus seed oil ; CLSO (125mg) and CLSO(250mg) were administered orally for 10 days in rats and compared with standard silymarin (100 mg/kg) orally. The results showed significant decrease in serum ALT, AST and ALP levels treated groups which were increased due to CCl4 induced liver damage are comparable with standard drug. Histopathological study of liver tissue ravels the hepatoprotective activity of Citrullus lanatus seed oil.