In pharmaceutical field various types of dosage forms are present and discovered continuously but some dosage form are have some solubility, stability or any other issues as per BCS classification system so these problem are overcome by using the formation of some solid dosage form like pharmaceutical cocrystals. During formation of pharmaceutical cocrystal molecules structure are important like hydrogen bonding, Crystal Engineering, Van der Waal‟s Interactions, Interaction involving π-system, Van der Waal‟s Interactions, and Supramolecular synthon etc. In supramolecular synthons certain types of bonding between the functional group like acid-acid, acid-pyridine, pyridine- pyridine etc. Formations of cocrystal are different techniques based on requirement of study. Basically use solvent evaporation, solvent assisted grinding, hot melt extrusion, slurry method, anti-solvent, cooling method etc. use to form pharmaceutical cocrystals. In pharmaceutical cocrystal contain API and Cocrystal coformer are present and theses final cocrystal characterized by the different techniques like SCXRD, PXRD, DCS,FTIR and NMR. Cocrystal is basically important to improve the solubility, bioavailability, stability, and dissolution rate of pharmaceutical dosage form.

Meditation is a practice where an individual uses a technique – such as mindfulness, or focusing their mind on a particular object, thought or activity – to train attention and awareness, and achieve a mentally clear and emotionally calm and stable state. Meditation, according to the spiritual meaning of the term, is not a process of the mind, but of the spirit. It goes through two stages: the preliminary one which can be defined as concentration, and the final one which can be called contemplation. Contemplation consists of gathering our attention with devotion in God, and raising it to one's own focal Center in the body. Mystics, Saints and Masters call this Center with different names. Christ calls it the single eye (aplus in the Greek text, Mathew 6:22) and St. Agustin calls it the "eye of the soul" (Confessions 7:10), while in the East it is called the third eye, or "tenth door" in order to distinguish it from the nine openings of the body (eyes, ears, nostrils, mouth and the two lower openings) tied to the plane of the senses. With the awakening of the "eye of the soul" or inner eye, the human soul may contemplate the Light of God, an experience which is common to the major mystics and Saints, both Christians and non-Christians of the East and the Middle East. Thus, all the Scriptures affirm that God is Light. Saint Agustin and many other Saints actually speak about the manifestation of God as Light. The human soul also has an inner ear with which it can tune into the Divine Power or Word vibrating in the entire creation, the sacred creative Sound. The Divine manifestation (or Holy Ghost), in the two forms of Celestial Lightand Sound, was experienced by the Apostles at Pentecost (Acts 2:2-4).

The plants worldwide used as a traditional medicine for treating of several disorders. Many biological activities have been achieved by a large number of secondary metabolites which extracted from these medicinal plants. The bioactive compounds presented in a different concentration in this plant family according to the reagent used for extraction. In this study we concentrate on three species from the family Asteracea which collected from a specific area in Libya. The active compounds have been isolated by using different types of reagent. Also in this research, we have summarized the pharmaceutical prospecting of natural compounds such flavonoids, sesquiterpenes, fatty acids, lignans, sterols and other metabolites isolated from the genus Amberboa, Anacyclus and Anvillea and their progresses in biotechnological applications as pharmaceuticals for the three species.