DOI: 10.36347/sjams.2019.v07i02.053

Pages: 693-695

Alcohol has now become one of the major socio - medical problem due to its excessive consumption in the world. Alcoholism is a major health problem in India and a high mortality rate is seen among Alcoholic liver disease patients. It is a reliable diagnostic marker of alcohol ingestion which is one of the most sensitive biochemical markers of alcoholic liver disease. This is a case control study carried out at a government tertiary care hospital in north Tamilnadu with a total study population of 120 subjects. Out of 120, 40 were healthy controls and 80 were alcoholic liver disease patients divided into two groups, alcoholic hepatitis in group I and alcoholic cirrhosis in group II. A significant correlation in the level of serum GGT is observed in alcoholic hepatitis (231.50±38.63) and alcoholic cirrhosis (91.73±15.76) when compared with the normal subjects (17.88±0.84) with p value (p<0.05). Among the alcoholic hepatitis and the alcoholic cirrhosis patients both shows a raise in serum GGT level, but its level shows a fall in alcoholic cirrhosis patients. Measurement of serum GGT appears to be a sensitive marker of alcoholic liver disease.