DOI: 10.36347/sjmcr.2019.v07i05.016

Pages: 363–365

Leigh syndrome (also called Leigh disease and subacute necrotizing encephalomyelopathy) is a rare inherited neurometabolic disorder that affects the central nervous system. We report a case with hypoactive with paucity of limbs movement, weak crying, poor feeding, developmental delay, decelerated head growth and abnormal eye movement described as oscillatory non rhythmic eyeball movement. Magnetic resonance imaging showing signal intensity changes bilateral in the globus balledi, thalami and the midbrain, mild Atrophic brain changes that lead to the diagnosis of Leigh syndrome.