DOI: 10.36347/sjmcr.2023.v11i09.004

Pages: 1583-1586

A 60-year-old man in reasonably good overall health presented with hematemesis and melena, along with chronic epigastric pain suggestive of an ulcer, without vomiting or fever. Clinical examination revealed epigastric tenderness, and laboratory tests showed anemia. Abdominal CT scan revealed thickening of the gastric wall, and esophagogastroduodenal endoscopy identified a giant gastric ulcer measuring 50 mm in diameter at the antral level. The initial series of multiple and deep biopsies did not indicate any signs of malignancy. The patient was treated with a double dose of proton pump inhibitors (PPIs), and an endoscopic follow-up after six weeks showed no clinical or endoscopic improvement. The second series of biopsies after treatment was also negative. Partial gastrectomy was performed, and histopathological examination of the resected specimens confirmed a benign gastric ulcer measuring 50 mm at the antre level.