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Scholars Journal of Applied Medical Sciences | Volume-8 | Issue-03
A Review on Hereditary Palmoplantar Keratoderma
Shivanu Mathon, Manu Singh
Published: March 7, 2020 | 98 143
DOI: 10.36347/sjams.2020.v08i03.011
Pages: 821-826
PPK require a precise diagnosis to determine the underlying defects, to know the predisposition for internal malignancy and for proper genetic counselling. The disorder can be diffuse (non- transgradient or transgradient) or focal loclised to pressure points. Non-transgradient PPK do not extend beyond the palms on the hands and the sole on the feet while Transgradient PPK extend beyond the palms and soles on their dorsal aspects and to flexor aspect of wrist. Skin around the mouth, eyes, nose, and over the elbows and knees may also be affected. Precise classification of disease helps in choosing the appropriate therapeutic modality.