DOI: 10.36347/sasjs

Pages: 152-156

Extra osseous ewing sarcoma is rare which mainly arise in paravertebral soft tissue and associated with CNS and ewing sarcoma of abdominal viscera is very rare. Only 14 to 18 cases of EES/pPNET arising in the pancreas have been reported so far in literature. We report a case 22 year boy presented with 15 days history of pain and lump abdomen. CT shows 18 *12cm mass in head of pancreas with central necrosis. CT scan showed no signs of metastatic tumor spread. Whipple procedure done for this patient, diagnosis of ewing sarcoma was confirmed by histology and immunohistochemistry.on IHC tumor was positive foe nuron specific enolase, KI 67 and MIC-2 and negative for pancytoceratin and progesterone. After surgery all margin was negative 8 LN was removed which was negative for metastasis. Patient has taken chemotherapy (6 cycle of VAC-vincristine adriamycine cyclophosfamide) and doing well after 6 month of operation .CT after 3 month of surgery was normal there was no evidence of disease .so any pancreatic mass which grows rapidly and patient present with short history we should think about PNET/ES and consider it as a differential diagnosis.