DOI: 10.36347/sjmcr.2020.v08i02.015

Pages: 161-164

Ménétrier’s disease is an infrequent hypertrophic disease of the stomach associated with hypoproteinemia of unknown etiology. This disease is considered to be premalignant since 10-15% of affected individuals develop gastric cancer. We report the case of a malignant degeneration of Ménétrier disease associated with gastric polyposis in a 60-years-old man who had received a diagnosis of Ménétrier’s disease 6 years previously and who was found to have advanced antral gastric cancer during the follow-up. We provide an update on the optimal therapeutic approach, which has not been clearly defined to date.