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Scholars Journal of Medical Case Reports | Volume-2 | Issue-03
Vanishing Bone (Gorham’s) Disease of the Mandible: A Case Report
Abdulai A E, Nuamah I K., Avogo D, Konadu Akua B.
Published: March 29, 2014 |
112
148
DOI: 10.36347/sjmcr.2014.v02i03.023
Pages: 183-187
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Abstract
Vanishing bone disease (VBD) is a rare, chronic condition of massive osteolysis characterized by proliferation
of vascular channels, and leading to resorption and progressive disappearance of the affected bone. Since its first
description by Jackson in 1838, 150 or more cases have been described in the literature, but only a very few of these are
reported in the jaws. The exact cause of the disease is not known and its natural history and prognosis unpredictable. We
report here, a case of VBD affecting the mandible of a young Ghanaian man who initially presented with acute severe
toothache and Trismus, of sudden onset, that progressed to unusually severe chronic pain similar to neuralgic pain
involving the right inferior alveolar nerve.