DOI: 10.36347/sjams.2016.v04i05.014

Pages: 1515-1518

Colorectal adenocarcinoma may demonstrate familial association with cancers at other sites. Herein, we reported a case report with SCC of the skin and colon cancer in the West of Iran. On July 2015, a 44-year man referred to the Clinic of Gastroenterology with complaints of weight loss,anorexia, weakness, lethargy and mild persistent pain of right flank since 2 months ago. After colonoscopy, the pathology report showed adenocarcinoma of the colon. On August 2015 after ileocolectomy, he was treated with Xeloda and Oxaliplatin. On October 2015, one papule was appeared on the right buttock and then was grown and ulcerated. After 5 months, the size of it increased up to 7cm. The pathology report of incisional biopsy showed well differentiated SCC with 4.5mm tumor thickness. Although, Lynch Syndrome was not confirmed in our case with immunohistochemistry and genotyping association of adenocarcinoma of the colon with SCC of the skin with criteria such as rather young age of patient, right-side location, mucinous feature and tumor infiltration of lymphocytes may be suggestive for further evaluation of the patient and his family with low cost tests such as occult blood in areas which high cost tests are not available or can’t be used.