The effect of EMF radiation emitted from mobile phone are many health related effect, the exposure to electromagnetic field radiation can penetrate deep into organic tissue and get absorbed producing many harmful effect in human body. Brain is involved in very important functions of the body and EMF might have damaging effect on its different parts. Exposure to EMF radiation has been observed to cause increased free radical production in cellular environment and damage the neurons in the Central nervous system.

Jatropha pandurifolia is plant belonging to family Eurphorbiaceae, and native to West Indies, and mostly used as an ornamental plant. Number of biological activities have been reported like: antibacterial, antifungal, antioxidant, cytoxic, insecticidal activities, and traditional uses of this plant like -cancer, rheumatisms, eczema, purgative and ring worm. The main objective of this review is to cover the biological activities and chemical constituents derived from this and provide insights and further investigate the plant for further study to introduce new components that would lead to production of effective phytomedicine.

Benzimidazole nucleus plays an important role in several categories of clinical agents such as antimicrobials, antivirals, antiparasitic, anticancer, anti-inflammatory, antioxidants, proton pump inhibitors, antihypertensives, anticoagulants, immunomodulators, hormone modulators, CNS depressants, and antidiabetics, etc. Many researchers coin it as a crucial moiety for the development of innovative therapeutic agents. Wide-ranging substituents on the benzimidazole nucleus show a varied spectrum of biological activities. In order to understand the current position of the benzimidazole nucleus in medicinal chemistry research, this review summarized the chemistry as well as pharmacological activities of benzimidazole scaffold. This discussion will further help in the development of novel benzimidazole compounds.

Rhododendron is genus of 1024 species of woody plant belongs to family Ericaceae. Mostly found in Northern Himalaya region. In India it commonly known “burans”. Plant has been proven to possess ant proliferative, antiinflammatory, antibacterial, immunomodulatory and antioxidant due to the presence of flavonoids, glycosides and triterpenoids. Traditionally used in cold, headache, and skin disease.

Although canagliflozin has been successfully used for the treatment of type 2 diabetes since its introduction in 2013, it has been continuing in research for the treatment of various diseases. The most common form of diabetes is type 2 diabetes and it was found that 95% of the people were suffering from this disease. Therefore, this review covers the pharmacokinetics and pharmacological effects of canagliflozin. It is hoped that this review will open the new gateways of research to achieve new rational approaches for more potent, less toxic and more therapeutically effective agents using canagliflozin.

A simple, accurate, precise and rapid reversed phase high performance liquid chromatography (RP-HPLC) method had been developed and subsequently validated for the simultaneous estimation of metformin HCl and sitagliptin phosphate in bulk & tablet dosage form. The proposed method was based on the separation of the two drugs in reversed phase mode using C18 (4.6 × 250mm, [5µ particle size]) analytical column. The optimised mobile phase consisted of phosphate buffer (pH adjusted to 3.11 using o-phosphoric acid): Acetonitrile in the ratio of 850:150. Flow rate was kept at 1ml/min. The simultaneous estimation was carried out at detection wavelength of 206nm using variable wavelength detector. Both drugs metformin HCl and sitagliptin phosphate were resolved and retained at 10mins. This method was statistically validated as per ICH guideline for analytical method validation.

Herbal formulations have growing demand in the world market and the plants have been reported in the literature having good anti-microbial, anti-oxidant and anti-inflammatory activity. In this study cream was formulated based on the anti-oxidant potential of herbal extracts and its evaluation. The cream was formulated with Licorice oil, Cinnamon oil, of different concentrations namely F1, F2, F3. The cream was stable during stability studies according to ICH guidelines 30±2 0C/50±5% RH and 40±2 0C/75±5% RH for two months. The evaluations of all formulations were done on different parameters like pH, spreadability, stability etc. Formulations F2 and F3 showed good spreadability, good consistency, and homogeneity with good appearance, pH, and no evidence of phase separation and ease of removal. The formulation F2 and F3 shows no redness, edema, inflammation and irritation to the skin during irritancy studies. These studies suggest that the composition of extracts and base of cream of F3 is more stable and safe, it may produce synergistic action. It can be concluded that herbal cream without side effects having anti-oxidant property can be used as provision of a barrier to protect the skin and avoid aging of the skin.

To investigate the anti-nociceptive effect of fruit pulp of Feronia elephantum Corr. in mice. The analgesic effect of the methanolic extract of fruit pulp of Feronia elephantum corr. were studied Acetic acid induced writhing test in mice. The methanolic extract exhibited anti-nociceptive activity against the acetic acid writhing test. The analgesic effect of methanolic extract might be through peripheral mechanism and thus justified its folkloric use in the treatment of rheumatism pain.

Ornamental plants are commonly known for their excruciating beauty and meant to decorate the gardens, lawns, streets and roadside areas. Nowadays these ornamental plants are used as herbalism. This review article represents one of such ornamental plant, Hamelia patens native to American subtropics and tropics. Its native range extends from Florida in the southern US to Argentina. Hamelia patens belong to the coffee Family (Rubiaceae). It is growing worldwide in warm, moist areas and can tolerate the extreme temperature. It is commonly known as firebrush, hummingbird bush and used long before prehistoric time as they are able to prevent, treat or even cure human ailments. Hamelia patens is a superb plant which has inflammation, analgesic, antimicrobial, myometrium contraction, hypoglycemic effect, leishmanicidal activity, anti-diarrheal, anthelmintic, antidepressant, hepatoprotective, Antiurolithiatic, diuretic, wound healing, anti-oxidant and antinociceptive like effect. All these activities are due to the phytoconstituents present in roots, leaves, stems, and bark. Fruit of H.patens is edible. In this article, we discussed chemical constituents and medicinal uses of Hamelia patens.

In the year 2012 total 56 million deaths were recorded globally, out of which NCDs constituted 38 million deaths that are 67.85 %.CVDs contribute to a major portion of death caused by NCDs. An estimated 17.5 million people died from CVDs in 2012, representing 31% of all global deaths. Of these deaths, an estimated 7.4 million were due to coronary heart disease and 6.7 million were due to stroke. According to Million death study CVD are the major cause of death in INDIA (1.8-2.0 million per year). There are various risk factors associated with CVDs; they can be classified in to local and systemic factors. Systemic factors are further divided in to modifiable and non modifiable factors. Modifiable factors consist of physical inactivity, smoking and many others whereas non modifiable factors consist of gender, age and genetic predisposition. The main objective of this research survey was to establish role of stress in development of CVDs and to make people about stress and its relationship with CVDs and other diseases. There are many factors which are associated with development of cardiovascular disease and stress is one of them, stress is both harmful and useful for the body as small amount of stress is also necessary to maintain consciousness of an individual. If stress level is increased and if remains for a long duration it may cause affect to various body organs like brain, kidney, GIT system (stomach ulcers), thinking and memory problems, sleep disorders and which may even lead to death. In this research survey a questionnaire of 13 questions was used to collect data from population of 120 people out of which 103 people’s data was screened out and analyzed, it consist of both male and female and people of different age group and occupation. In results it was found that most of the population knows the meaning of stress, but very less follow any kind of physical activity on the daily basis

Digital marketing relates to the usage of different channels on the digital platform to reach the potential buyers via channels like: social media marketing, multimedia advertising, websites and online search engines. Digital Pharma Marketing encompasses all the digital channels and tools used for promotion of a drug or a service. Digital pharma promotional tools not only are effective but also save time, are more informative and convenient and also reduce paper cost. With the advancement of digital pharma marketing there is an ease of communication between the patients, doctors and the healthcare organizations. This article focuses on evaluating the various kinds of Conventional and Digital marketing and promotional tools, their advantages and disadvantages and its impact on pharmaceutical industry

Moxidectin is a macrocyclic lactones derivative are probably the anti-parasitic agents most widely used in the treatment of food producing animals, poultry, aquaculture and crops. A number of alternative products such abamectin, doramectin, emamectin, eprinomectin, milbemycin and selamectin, have been marketed since. The increase in the number of macrocyclic lactones drugs, there has been a steady increase in the number of published analytical methods for determination of their residues. Methodologies for determination of moxidectin residues in biological matrices are described in terms of extraction and clean-up methods used for different matrices. Detection systems for determination of moxidectin residues are discussed with a particular emphasis placed on new developments in screening technologies and different chromatography with fluorescence or mass spectrometry.

Fast food in convenient and easy to prepare food and contains low nutritious and unhealthy ingredient. This paper is focused on the effect of fast food on health and associated problems on people from a specified area. Questionnaire had utilized as a data collection instrument. SPSS had used for tabulation and graphs and other parametric and nonparametric tests. Result showed that youngsters spend more money on fast food because of taste and showoff also. People prefer fast food at their workplace and student prefer at schools and colleges due to their busy schedules. In this research mostly females takes part and total 58.7% are females and 41.3% are males. Among all 150 people 42.7% people from the age group of 20-35 years olds are more interested in taking of fast food. 46.7% people of total population are used to of fast food from more than 10 years and mostly prefer pizza; momo’s and noodles as fast food. Females are more conscious about the health, weight monitoring, and also aware about the nutritional value of the fast food. Obesity and liver disease are most common and prone to those people who are consuming fast food. Work out like walking, cycling and gym reduce the effect of unhealthy food and monitoring of weight also helps to maintain the effect of fast food on health. Female are more prone towards piles and liver disease and male towards obesity. Among all the people included in research age group of 20-35 are more aware about disease caused by fast food and ingredient of fast food. 68.7% people are used to of working out daily by different mediums and it should be suggested that there is a need to focus on nutrition counseling to facilitate the intake of healthy foods.