Lateral periodontal cyst is a rare developmental odontogenic type of cyst. It is being frequently diagnosed as an incidental radiographic finding, presenting as a well circumscribed round or tear shaped radiolucent area between the roots of vital teeth. It is often misdiagnosed as one of the lesion of endodontic origin. This case reports of a classical example of lateral periodontal cyst describing its clinical, radiological and histological features representing that the final diagnosis must be based on histopathological examination.

Background: The aim of this study was to assess the knowledge of dental office environment during the pre- and post-COVID-19 pandemic, and attitude towards seeking dental treatment and care in a sample of participants who have access to dental care. Materials and Methods A structured 42 question survey questionnaire was utilized as the study instrument. The survey addressed three areas of knowledge regarding infection transmission in dental clinics, infection control measures used in dental clinics, and general knowledge about COVID-19. Descriptive statistics were presented. Associations between knowledge and attitude scales and demographic characteristics were evaluated. Results A total of 757 participants completed the survey. The study found that around one half of the respondents before the start of the COVID-19 pandemic would be regular visitors to the dentists. Approximately half reported visiting the dental clinic during the COVID-19 outbreak. Respondents reported the main sources of information they used to obtain information about the COVID-19 pandemic from official websites. There was a positive relationship between higher income and educational levels and greater knowledge concerning infection transmission in dental clinics and general knowledge about COVID-19. A significant positive relationship was found between the level of knowledge concerning infection transmission in dental clinics and agreement with the additional control measures taken during the pandemic. Conclusions The study population did not have an accurate understanding of the routes of transmission of the COVID-19 virus yet had a fair amount of knowledge about general infection control measures. Poor knowledge was associated with an increased perceived sense of security regarding seeking dental treatment among respondents.

Background and objectives: Head and neck carcinomas are the biological heterogeneous group of cancers, of which oral cancer is the most common. Ninety percent of oral cancers are squamous cell carcinomas originating from the mucosal epithelium carcinogenesis. Oral squamous cell carcinoma (OSCC) is one of the most prevalent cancers worldwide. The transformation of the normal epithelial cell into a tumor cell depends upon certain changes that happen at the cellular and molecular level which will help in its survival and proliferation. The basement membrane will show invasion by these altered tumor cells into the connective tissue stroma and then their subsequent spread and metastasis, which is an important prognostic indicator. Laminin-5 is a protein which is found to be associated with a migratory phenotype in epithelial neoplastic cells and also the stromal myofibroblasts play a key role in tumor invasion, due to its ability to modify the extracellular matrix. Aim: Laminin-5 (Ln-5) is the major component of the basement membrane and is involved for tumour progression. Alpha-smooth muscle actin (α-SMA) is an isoform of actin, positive in myofibroblasts and is an epithelial to mesenchymal transition (EMT) marker. EMT is a process by which tumor cells develop and are able to metastasize. Tumor cells progression is always followed by alteration in the cell composition and extracellular matrix .Therefore the aim of this study is to detect and evaluate the expression of laminin5 gamma2 and α-SMA in OSCC and to evaluate the association of density of stromal myofibroblasts with tumour budding intensity. Materials and methods: Thirty paraffin embedded tissue blocks of clinically diagnosed and histopathologically confirmed cases of OSCC were evaluated .In this we have divided them into10 well differentiated OSCC,10 moderately differentiated OSCC and 10 poorly differentiated OSCC for laminin-5 and α- smooth muscle actin (SMA) using standard immunohistochemistry technique. ....

The purpose of this study was to see how a short-term application of calcium hydroxide affected the dentine strength of adult human permanent teeth. Materials and methods: We selected 15 disease-free permanent mandibular premolars extracted from humans. The root canals were prepared using rotary equipment and divided into three groups at random. In one group, the root canals were filled with a calcium hydroxide paste (RC Cal) and in another group the root canals were filled with a calcium hydroxide paste (NEO Cal). Canals of teeth in the control group were left empty. All teeth were stored in normal saline for 14 days and then coronal third root dentin cylinders were created by removing the crown and apical portions of the teeth. The compressive forces required to shatter the dentin cylinders were measured using an Instron machine (UNIVERSAL TESTING MASCHINE), and the data was analysed using the Anova test. Results: The calcium hydroxide-filled teeth had a considerably lower mean compressive force than the control teeth (P < 0.005). Conclusion: Teeth that had been exposed to calcium hydroxide for 14 days needed less compressive force to shatter root dentin cylinders. Further research is needed to see if impact testing will provide similar results.