Background: Pulmonary embolism is a potentially fatal disorder for which anticoagulation therapy improves the outcome. Aim is to study the clinical profile, diagnostic methods and management in patients with pulmonary embolism. Methods: Retrospective assessment of clinical features and management of 34 patients presenting with pulmonary embolism from January 2019 to December 2019 in the department of General Medicine at SDM CMS & H tertiary care centre. Results: 34 patients who were diagnosed to have pulmonary embolism with a mean age 51.3 years were included in the study. Dyspnea (30) and lower limb swelling were predominant symptoms. The most common ECG finding was sinus tachycardia in all patients followed by Q3T3 in 11 patients followed by RBBB in 9 patients followed by S1T3 and S1Q3T3 in 5 patients and T wave inversion in v2-v5 in 3 patients. 32 patients showed positive D dimer levels. 8 patients had hypoxia on arterial blood gas analysis. 15 patients had lower limb proximal deep vein thrombosis. Echocardiography was done in all patients. 26 patients had pulmonary arterial hypertension and 23 patients had RV dysfunction. Conclusion: Pulmonary embolism is a common problem and can be easily diagnosed provided it is clinically suspected. Early diagnosis and aggressive management is the key to successful outcome.

Obesity is a global disease. This study explores the links between obesity and morbidity and mortality in COVID-19. The coronavirus disease 2019 (COVID‐19) is caused by a single‐stranded RNA virus. Recent data suggest that people with obesity are at increased risk of severe COVID-19. Obesity increases risk for hospitalization, ICU admission, Invasive Mechanical Ventilation requirement and death among patients with COVID-19. This study also highlights the pathways by which complications arise in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A hyperinflammatory reaction through the excessive release of cytokines, a condition known as "cytokine storm is responsible for increased morbidity and mortality. We also discuss how severe acute respiratory syndrome coronavirus 2 penetrates human cells through direct binding with angiotensin-converting enzyme 2 receptors on the cell surface. Angiotensin-converting enzyme 2 expression in adipose tissue is higher than that in lung tissue, which means that adipose tissue may be vulnerable to COVID-19 infection.

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of women of reproductive age. Anti-Mullerian hormone (AMH) has a glycoprotein dimer structure and is a member of the transforming growth factor-β (TGF-β) family. AMH is produced by the granulosa cells surrounding preantral and antral follicles and has an important role in the development and maturation of follicles. Several studies have suggested that AMH serum levels may be a marker for polycystic ovary syndrome (PCOS). Serum AMH has also demonstrated its utility in the treatment of infertility. Objective: To assess relationship of AMH level with ovarian response in Polycystic Ovary Syndrome (PCOS) patients. Methods: This is a cross sectional comparative study which was held at Sylhet women’s Medical college from 2018 to 2019. Result: In this study 45 respondent had participated. For statistical analysis of this study AMH divided by two sub groups Group A (<8) and Group B (8<) and study found that 50.7% respondent had AMH which is Group A (<8). This study also revealed the negative correlation between AMH and follicle size (r= -0.288). On other hand AMH Group have positive correlation between LH (r = 0.238. Besides follicle size have positive correlation with ET (r=0.044) which is statistically significant. Conclusion: From this study it is easily understandable that AMH plays an important role to predict ovarian response to ovulation education in Polycystic Ovary Syndrome (PCOS) patients.