Original Research Article
May 21, 2022
Acquired Aortic Arch Anomalies and Right Radial Approach: Practical Solution
A. Zbitou, R. Zerhoudi, A. Bouzerda, A. Khatouri
Sch J App Med Sci | 798-802
DOI : 10.36347/sjams.2022.v10i05.021
Introduction: Morphological abnormalities of the arch and its branches can also be acquired with the aging of the population and cardiovascular risk factors. These arteries become deformed, dilated, and curved, making coronary exploration by the right radial approach very delicate. Objective of the study: To propose a new strategy for the approach of the right radial consisting of the use of a long, hydrophilic-coated armed introducer instead of the usual 7 cm introducers, which will allow us to compensate for the change of approach. We hope to reduce the time of scopy, the complications and the quantity of contrast medium used, through a retrospective descriptive study including 08 patients. Result: The mean age in the group was 77 years with a male/female sex ratio of 7. - The clearly predominant cardiovascular risk factor apart from age was hypertension in all groups: 62%. Eight patients with sinuosity and long armed introducer: seven with 6 Fr and 90 cm long, one with a long introducer of 100 cm and 4 Fr. The use of a long-armored introducer made it possible to perform coronary angiography in 8 patients with extreme sinuosity and coronary dilatation for the needy without any complications. The average scanning time is eight minutes for a coronary angiography. Without increasing the amount of contrast medium. In addition to the success of the coronary angiography, a control of the left mammary bypasses in two patients with tortuosities of the right subclavian and a very tortuous path could be carried out. No per-procedural complications were reported. These path anomalies were overcome with excellent support and ease through the use of the long-armed introducer. Discussion and conclusion: Anomalies of the aortic arch make coronary angiography via the right radial approach a difficult procedure. The use of a long armored hydrophilic coated introducer via the right radial approach is possible, effective and safe. It is a promising technique that is .............
Original Research Article
May 20, 2022
Improvement in some Reproductive Parameters of Male Wistar Rats Administered with Leaf Extract of Eugenia uniflora
Constance I. Nkpurukwe, Chibuike Obiandu, Bright I. Owhorji, Abiye Tamuno-Opubo, Adesua C. Obiandu, Karibo Okari
Sch J App Med Sci | 793-797
DOI : 10.36347/sjams.2022.v10i05.020
This study was designed to evaluate the effect of hydro-methanol leaf extract of Eugenia uniflora on lead-induced reproductive toxicity in male Wistar rats. The male rats used for the study were divided into 5 groups of 6 animals each. Group I was the negative control group which received no treatment. Group II was the positive control which received 5 mg/kg BW Lead daily, while Group III received 5 mg/kg BW of Lead and 200mg/kg BW of extract., Group IV received 5 mg/kg BW of Lead and 400mg/kg BW of extract and group V received 5 mg/kg BW of Lead and 800mg/kg BW of extract. The administration was by oral gavage once daily for 30 days. At the end, animals were sacrificed under light chloroform anesthesia. Blood samples were collected into plain bottles for hormonal assay. The epidydimis was located with a small incision on the abdomen and semen sample was collected for analysis of sperm parameters. The data was analysed by applying one-way analysis of variance (ANOVA) using the SPSS version 23 software. Results of this study showed that extract of Eugenia uniflora significantly increased the level of serum testosterone and the percentages of viable sperm cells, sperm cells with normal morphology and actively motile sperm cells as well as, sperm count. The extract ameliorated lead induced reproductive toxicity. The result therefore, show that the extract improves sperm quality and quantity and protects the male reproductive function from the hazardous effect of environmental toxicants such as lead.
Viral Hepatitis B and Chemotherapy
I. Elkoti, R. Laroussi, R. Berreda, A. Benhamdane, O. Mohammed, T. Addajou, S. Mrabti, S. Sentissi, F. Rouibaa, A. Benkirane, H. Seddik
Sch J App Med Sci | 790-792
DOI : 10.36347/sjams.2022.v10i05.019
Patients with chronic hepatitis B treated with chemotherapy or immunotherapy are at risk of viral reactivation, which can have serious or even fatal consequences . Patients treated with chemotherapy for haematological disease have a known risk of hepatitis B virus (HBV) reactivation with an estimated incidence of 14-72% . The majority of chemotherapy drugs can induce HBV reactivation in patients with HBs-positive antigen . HBs testing should therefore be recommended prior to chemotherapy. Preventive antiviral treatment will reduce the risk of HBV reactivation.