Introduction: Biological wound healing consists of a cascade of cellular and molecular events. Healing processes can be influenced by a variety of factors, both local and systemic. Cutaneous and oral wounds can be either accidental or surgical. Biochemical components contained in animal or plant origin substances may promote the repair of the integrity of injured tissues by supporting blood clot formation, stimulating neo-angiogenesis, protecting the wound from infection, and inducing connective tissue formation. Topical gel applications based on mucus secreted by various snail species, alone or combined with other therapeutic options, may accelerate tissue repair and promote tissue normalization after surgical incisions, traumatic wounds, periodontal and peri-implant injuries, and infections. Materials and Methods: A literature search of the electronic databases PubMed and Google Scholar was conducted to identify which scientific articles reported the clinical use of snail slime gels as bio-stimulants in adjuvant tissue repair processes. Specifically, our focus was to identify whether clinical cases and scientific papers proposed Gelenzyme® as an adjuvant in oral wound or injury healing processes as we did in our clinical practice. Results and Discussion: Three papers and/or academic posters presenting clinical cases were identified. Besides, we decided to report our own clinical case of a patient who presented with a mechanical complication of a single implant-supported prosthetic crown. Crown fracture, detachment from the abutment and exposure of the emergent abutment in the oral cavity resulted in the adjacent lingual border erosion. The traumatic lingual injury was treated with Gelenzyme® Clinical healing appeared more rapid and rather successful with reduced local symptomatology and the absence of adverse reactions. The number and diffusion of reported clinical cases using Gelenzyme® are still limited. Conclusion: Pharmacological properties such as ...........

Lipoma is a common benign mesenchymal tumor of soft-tissue. In the oral cavity lipomas represent 0.5 to 5% of benign tumors, however, central intraosseous forms are exceptional, mainly at the mandibular bone. Most of intraosseous lipomas are asymptomatic and discovered on x-ray. Symptoms of intraosseous lipoma vary depending on the location and size of the tumor. Radiographically, the lesion generally appears as a well-circumscribed radiolucent image. In fact, the diagnosis of intraosseous lipoma of the mandible can be problematic due to its rarity and clinical and radiological similarity to many other radiolucent lesions, therefore, histopathological examination is always essential. The treatment of choice for intraosseous lipomas is the surgical enucleation of the lesion. The article presents a case report of intraosseous lipoma of mandible in a 58-year old male. Diagnosis, differential diagnosis and treatment of this benign tumor are discussed based on a review of the current literature.

Jejunoileal atresia (JIA) and stenosis are the most common congenital anomalies of the small intestine and are a major cause of intestinal obstruction in neonates. The traditional classification of JIA proposed by Grosfeld included 4 subtypes of which type IIIB, or apple-peel atresia, is characterized by a proximal atretic jejunum and a distal segment of spiralled bowel that terminates at the cecum. These patients are at increased risk for short bowel syndrome and subsequent intestinal failure. We hereby describe a case of a neonate with JIA who was initially found to have a type IIIB atresia but there was a variation as she had a length of normal small bowel and mesentery proximal to cecum attached distal to spiralled segment of bowel. Surgical correction proceeded with minimal resection and primary anastomosis. She recovered well from this procedure, tolerated full enteral nutrition by mouth, and displayed good weight gain at outpatient follow-up. Due to the unique anatomy of the gastrointestinal tract in this case report, we propose the addition of a new class of JIA, type IIIC, to better reflect its prognostication and surgical management.